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Diseases/Injuries of Serum therapy
News
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2020.09.05
- For medical professionals
A comprehensive review (including serum therapy) for marine envenomation bite wounds has been prepared.
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2020.08.21
- For All
English version updated! (English version of serum therapy)
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2020.08.05
- Blog
The future of serum therapy is described.
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2020.05.31
- For All
Commented on serum therapy for new coronavirus infection.(Part 2)
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2020.03.22
- For All
Commented on serum therapy for new coronavirus infection.
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2020.03.01
- Blog
Serum therapy in general is explained in an easy-to-understand manner.
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2020.02.28
- For All
We have created a website.
Serum therapy
Currently, the only facility in Japan capable of producing antitoxin and antiserum is KMB (formerly the Research Institute for Chemotherapy and Serotherapy, Kumamoto).
In the case of equine serum, equine immunoglobulin is purified from the serum or plasma obtained by immunizing equines and collecting their blood, which is then filled into vials and formulated.
Production process of
bovine antitoxin preparation (example)
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Bovine immunization process
- Immunization (basic, additional)
- Blood collection
- Serum and plasma separation
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Antivenom purification process
- Pepsin digestion
- Salting out, dialysis
- Stock solution preparation
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Manufacturing process
- Final bulk preparation
- Filling
- Lyophilization, sealing
